Shares of Bristol-Myers Squibb Co (NYSE:BMY) ended Friday session in red amid volatile trading. The shares closed down -0.41 points or -0.72% at $56.35 with 34.00 million shares getting traded. Post opening the session at $56.93, the shares hit an intraday low of $55.11 and an intraday high of $56.93 and the price vacillated in this range throughout the day. The company has a market cap of $93.12 billion and the numbers of outstanding shares have been calculated to be 1.66 billion shares.
Bristol-Myers Squibb Co (BMY) announced that it will host a teleconference on Sunday, October 9, 2016, at 7:30 p.m. CEST (1:30 p.m. EDT) to discuss data presented at the European Society of Medical Oncology (ESMO) 2016 Congress in Copenhagen, Denmark. Company executives will provide an overview of data presented at the meeting, with a focus on the company’s Immuno-Oncology portfolio, and address inquiries from investors and analysts.
Investors and the general public are invited to listen to a live webcast of the call at: investor.bms.com, by dialing toll free (877) 258-2708 or international (647) 252-4456, confirmation code: 74677318. Materials related to the call will be available at the same website prior to the call. A replay of the call will be available beginning at 4:30 p.m. EDT on October 9, 2016 through 11:59 p.m. EDT on October 16. The replay can be accessed at investor.bms.com or by dialing (855) 859-2056 or (404) 537-3406, confirmation code: 74677318.
Shares of CTI BioPharma Corp (NASDAQ:CTIC) ended Friday session in green amid volatile trading. The shares closed up +0.002 points or 0.56% at $0.392 with 535,230.00 shares getting traded. Post opening the session at $0.40, the shares hit an intraday low of $0.39 and an intraday high of $0.40 and the price vacillated in this range throughout the day. The company has a market cap of $110.08 million and the numbers of outstanding shares have been calculated to be 282.72 million shares.
CTI BioPharma Corp (CTIC) on Aug. 29, 2016 announced top-line results from PERSIST-2, a randomized, controlled Phase 3 clinical trial comparing pacritinib, an investigational oral multikinase inhibitor, with physician-specified best available therapy (BAT), including ruxolitinib, for the treatment of patients with myelofibrosis whose platelet counts are less than 100,000 per microliter — a patient population with high-risk advanced disease. Three hundred eleven (311) patients were enrolled in the study, which formed the basis for the safety analysis. Two hundred twenty-one (221) patients who had a chance to reach Week 24 (the primary analysis time point) at the time the clinical hold was imposed and constituted the intent-to-treat (ITT) analysis population utilized for the evaluation of efficacy. Preliminary results demonstrated that the PERSIST-2 trial met one of the co-primary endpoints showing a statistically significant response rate in spleen volume reduction (SVR) in patients with myelofibrosis treated with pacritinib compared to BAT, including the approved JAK2 inhibitor ruxolitinib (p<0.01). Although the PERSIST-2 trial did not meet the other co-primary endpoint of greater than 50 percent reduction in Total Symptom Score (TSS), the preliminary analysis approached marginal significance compared to BAT (p=0.0791).
“Unlike patients with myelofibrosis who have normal baseline platelet counts where median survival is reported at 88 months, we recently reported from our institution’s experience that patients with severe thrombocytopenia (low platelets) had a median survival of about 14 months,” said Srdan (Serge) Verstovsek, M.D., Ph.D., Director, Clinical Research Center for MPNs at the University of Texas MD Anderson Cancer Center and principal investigator for the PERSIST-2 Phase 3 clinical trial of pacritinib. “These patients represent up to 30 percent of all myelofibrosis patients and an unmet medical need. Data from the PERSIST-2 prospective randomized, controlled trial is encouraging because we need an effective therapy to treat the most challenging patients with low platelet counts we see in our practice.”